A new research study prompts the increased immunity of ancient Africans to frequent threats of malaria. The researchers suggest that the ancient Africans have evolved with a more robust response to malarial inflammation.
Malaria is no longer a threat to the descents of those ancient Africans staying currently in the United States. As we all know that the genetic variants persist down the descents, the existence of those genetic variants in the African descents might affect the health disparities prevailing today.
A new research study focused on searching the cause behind different susceptibilities to illnesses by different ethnic background individuals. The findings of the present research study mark its online presence in ‘Plos Genetics.’ The study explores the trigger mechanism of the individual’s immune system to fight inflammation. The study was performed by an international research team of Roswell Park Comprehensive Cancer Center. Dr. Song Yao led the researchers to focus on the chemical messengers responsible for producing inflammation.
The factors such as age and lifestyle of the individual were ruled out from the study. The research team was victorious in the identification of genetic variants that establish a difference between those African descents and their counterpart European descent.
Genetic variant results in the loss of an antigen protein. This protein is named as the Duffy antigen protein. The loss of Duffy antigen proteins from the red blood corpuscles plays a crucial role in directing the RBC’s to the inflammation site. It also offers protection from Malaria.
Christine Ambrosone in a statement to Newsweek said, “Results from our study show differences in specific immune factors according to ancestry that likely arose as a result of selection for protection from some infectious diseases, such as malaria.” Christine Ambrosone is a senior author and a researcher at the Roswell Park Comprehensive Cancer Center.